Potassium Hydroxide → HCID 22998999, compound

HRID 1166673Notes

Reaction equation

[CH2:1]([N:3]([C:15]1[C:24]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:23][C:22]2[C:21]([CH3:33])([CH3:32])[CH2:20][CH:19]=[C:18]([CH3:34])[C:17]=2[CH:16]=1)[C:4]1[CH:14]=[CH:13][C:7]([C:8]([O:10]CC)=[O:9])=[CH:6][CH:5]=1)[CH3:2].[OH-].[K+]>>[CH2:1]([N:3]([C:15]1[C:24]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:23][C:22]2[C:21]([CH3:32])([CH3:33])[CH2:20][CH:19]=[C:18]([CH3:34])[C:17]=2[CH:16]=1)[C:4]1[CH:14]=[CH:13][C:7]([C:8]([OH:10])=[O:9])=[CH:6][CH:5]=1)[CH3:2]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 22218336HCID 22218336, compound2×

Product 1

HCID 22998999HCID 22998999, compoundYield 27%

Procedure

Following General Procedure E ethyl 4-[ethyl-(3-n-hexyloxy-5,5,8-trimethyl-5,6-dihydronaphthalen-2-yl)amino]benzoate (Compound 125, 0.036 g, 0.078 mmol) was saponified with KOH to give 0.0090 g (27%) of the title compound as a yellow oil.

Sources & evidence

ORD record: ord-b71b86f290fc4de1b1bd02fedb6927cd
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06613917B1

Reaction notes

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