Isopropyl iodide → HCID 22218326, compound

HRID 1166681Notes

Reaction equation

HRID 1166681 reaction equation
[Br:1][C:2]1[C:3]([OH:17])=[CH:4][C:5]2[C:6]([CH3:16])([CH3:15])[CH2:7][CH:8]=[C:9]([CH:12]([CH3:14])[CH3:13])[C:10]=2[CH:11]=1.I[CH:19]([CH3:21])[CH3:20]>>[Br:1][C:2]1[CH:11]=[C:10]2[C:5](=[CH:4][C:3]=1[O:17][CH2:20][CH2:19][CH3:21])[C:6]([CH3:15])([CH3:16])[CH2:7][CH:8]=[C:9]2[CH:12]([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 6362Isopropyl iodideHCID 22218215HCID 22218215, compound2×

Product 1

HCID 22218326HCID 22218326, compoundYield 43%

Procedure

Following General Procedure O, 3-bromo-5-isopropyl-8,8-dimethyl-7,8-dihydronaphthalen-2-ol (Compound 97, 0.36 g, 1.2 mmol) was reacted with 2-iodopropane to afford 0.18 g (43%) of the title compound as a clear oil.

Sources & evidence

ORD record
ord-70cf4f4d8c4f47a3b5f1ba5e0760c0bb
Source dataset
uspto-grants-2003_09
Patent number
US06613917B1

Reaction notes

Loading…