p-Xylyl bromide → HCID 22218252, compound

Participants

Reaction Steps

Following General Procedure O, 3-bromo-5-isopropyl-8,8-dimethyl-7,8-dihydronaphthalen-2-ol (Compound 97, 0.14 g, 0.49 mmol) was reacted with 4-methylbenzylbromide to afford 0.19 g (1 00%) of the title compound as ayellow oil. PNMR (300 MHz, CDCl3) δ 1.22 (d, 6H, J=4.5 Hz), 1.28 (s, 6H), 2.22 (d, 2H, J=4.7 Hz), 2.45 (s, 3H), 5.22 (s, 2H), 5.78 (t, 1H, J=4.5 Hz), 7.02 (s, 1H), 7.22 (d, 2H, J=8.8 Hz), 7.38 (d, 2H, J=9.3 Hz), 7.60 (s, 1H).

Provenance & Evidence