4-formylnaphthalene-1-carboxylic Acid → 4-[(3-Chloro-4-hydroxybenzoyl)hydrazonomethyl]naphthoic Acid

Participants

Reaction Steps

To a solution of 3-chloro-4-hydroxybenzoic acid hydrazide (1.53 g, 8.23 mmol) in DMSO (20 mL) was added a solution of 4-formylnaphthoic acid (1.65 g, 8.23 mmol) in DMSO (2 mL). After stirring the solution for 16 hr, the reaction was diluted with ethyl acetate (30 mL) and water (30 mL). A precipitate formed. The precipitate was collected, washed with hexane and dried to give the product as a white solid in quantitative yield.

Provenance & Evidence