6-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide → tert-butyl [5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[6-[4-[4-[[3-[3-carbamoyl-4-(3-methoxyanilino)-8-methylquinolin-6-yl]sulfonylbenzoyl]amino]phenyl]butoxy]hexyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethyl]-2-oxo-1H-quinolin-8-yl] carbonate
Reaction equation
[NH2:45][c:46]1[cH:47][cH:48][c:49]([CH2:52][CH2:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][N:63]([C:64]([O:65][C:66]([CH3:67])([CH3:68])[CH3:69])=[O:70])[CH2:71][CH:72]([O:73][Si:74]([CH3:75])([CH3:76])[C:77]([CH3:78])([CH3:79])[CH3:80])[c:81]2[c:82]3[cH:83][cH:84][c:85](=[O:99])[nH:86][c:87]3[c:88]([O:91][C:92](=[O:93])[O:94][C:95]([CH3:96])([CH3:97])[CH3:98])[cH:89][cH:90]2)[cH:50][cH:51]1.[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11](=[O:12])[c:13]1[cH:14][c:15]([S:19](=[O:20])(=[O:21])[c:22]2[cH:23][c:24]3[c:25]([NH:36][c:37]4[cH:38][c:39]([O:43][CH3:44])[cH:40][cH:41][cH:42]4)[c:26]([C:33](=[O:34])[NH2:35])[cH:27][n:28][c:29]3[c:30]([CH3:32])[cH:31]2)[cH:16][cH:17][cH:18]1>>[C:11](=[O:12])([c:13]1[cH:14][c:15]([S:19](=[O:20])(=[O:21])[c:22]2[cH:23][c:24]3[c:25]([NH:36][c:37]4[cH:38][c:39]([O:43][CH3:44])[cH:40][cH:41][cH:42]4)[c:26]([C:33](=[O:34])[NH2:35])[cH:27][n:28][c:29]3[c:30]([CH3:32])[cH:31]2)[cH:16][cH:17][cH:18]1)[NH:45][c:46]1[cH:47][cH:48][c:49]([CH2:52][CH2:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][N:63]([C:64]([O:65][C:66]([CH3:67])([CH3:68])[CH3:69])=[O:70])[CH2:71][CH:72]([O:73][Si:74]([CH3:75])([CH3:76])[C:77]([CH3:78])([CH3:79])[CH3:80])[c:81]2[c:82]3[cH:83][cH:84][c:85](=[O:99])[nH:86][c:87]3[c:88]([O:91][C:92](=[O:93])[O:94][C:95]([CH3:96])([CH3:97])[CH3:98])[cH:89][cH:90]2)[cH:50][cH:51]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-951fc5701fea45a8b026e88161f1db17
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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