HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Propylphenyl)boronic acid → N-[5-(4-propylphenyl)thiophene-2-sulfonyl]pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Propylphenyl)boronic acid | HCID 4100861 | — |
| Reactant | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| Product | N-[5-(4-propylphenyl)thiophene-2-sulfonyl]pyrrole | HCID 22998454 | 55% |
Reaction Steps
N-[5-(4-propylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 33C, from 4-propylphenyl boronic acid and N-(5-bromothiophenesulfonyl)pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as a white solid in 55% yield, m.p. 106-108° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613804B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-518fe9b6e18b4613ac2bf6f0a2b4046e |
| Source note | uspto-grants-2003_09 |