HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-(4-Methoxybenzyl)-benzo[b]thiophene-3-sulfonylchloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 2-(4-Methoxybenzyl)benzo[b]thiophene | HCID 22998384 | — |
| Product | 2-(4-Methoxybenzyl)-benzo[b]thiophene-3-sulfonylchloride | HCID 22998510 | — |
Reaction Steps
2-(4-methoxybenzyl)-benzo[b]thiophene-3-sulfonylchloride was prepared by the method of Example 40B with DMF (3.2 mmoles, 0.24 ml), sulfurylchloride (2.7 mmoles, 0.22 ml) and 2-(4-methoxybenzyl)-benzo[b]thiophene (1.6 mmoles. 0.4 g). Flash chromatography using 2% ethyl acetate/hexanes provided 0.19 g (33%) of a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613804B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-1484315ede1b418483ea761c7be39fe0 |
| Source note | uspto-grants-2003_09 |