HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-methylisoxazol-5-amine → Ammonium Hydroxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Reactant | HCID 22998416 | HCID 22998416 | — |
| Product | Ammonium Hydroxide | HCID 14923 | — |
| Product | HCID 23445439 | HCID 23445439 | — |
Reaction Steps
N-(4-bromo-3-methyl-5-isoxazolyl)-5-(3-tolyl)thiophene-2-sulfonamide was prepared in the same manner as described in the Example 117C using 2-chlorosulfonyl-5-(3-tolyl)thiophene and 5-amino-4-bromo-3-methylisoxazole. To obtain the ammonium salt of the final product, aqueous NH4OH was used (31% yield; hygroscopic).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613804B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-15b36d58214f41ce91786b4e8a04f894 |
| Source note | uspto-grants-2003_09 |