1-(Chloromethoxy)-2-methoxyethane → HCID 69983700, compound

HRID 1166956Notes

Reaction equation

HRID 1166956 reaction equation
[CH3:1][C:2]1[C:6]([CH3:7])=[C:5]([NH:8][S:9]([C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)(=[O:11])=[O:10])[O:4][N:3]=1.[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22]Cl>>[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22][N:8]([C:5]1[O:4][N:3]=[C:2]([CH3:1])[C:6]=1[CH3:7])[S:9]([C:12]1[S:13][CH:14]=[CH:15][CH:16]=1)(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 22998429HCID 22998429, compound

Product 1

HCID 69983700HCID 69983700, compoundYield 34%

Procedure

N-(methyoxyethoxymethyl)-N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide was prepared in the same manner as described in Example 32B using N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide and methoxyethoxymethyl chloride resulting in 34% yield. HPLC analysis of the crude oil obtained after workup showed that the oil was approximately 96% pure and so was used in the next step without further purification.

Workup

  1. customHPLC analysis of the crude oil obtained after workup
  2. customso was used in the next step without further purification

Sources & evidence

ORD record
ord-3dbda57afc534abbb80fc0117e11263a
Source dataset
uspto-grants-2003_09
Patent number
US06613804B2

Reaction notes

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