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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 116696Generated: October 31, 2026

2-Amino-5-(6-morpholin-4-ylpyridin-3-yl)thiophene-3-carboxamide → 2-{[6-Methyl-5-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl]amino}-5-(6-morpholin-4-ylpyridin-3-yl)thiophene-3-carboxamide

https://huagongshe.com/reaction/116696

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-(6-morpholin-4-ylpyridin-3-yl)thiophene-3-carboxamideHCID 59525734—
Reactant1-(6-Chloro-2-methylpyridin-3-yl)-2,2,2-trifluoroethanolHCID 59525938—
Product2-{[6-Methyl-5-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl]amino}-5-(6-morpholin-4-ylpyridin-3-yl)thiophene-3-carboxamideHCID 59525971—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-36231cca697c4e88a5b57574540a4dfe
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)