HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-methylisoxazol-5-amine → HCID 23445430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Reactant | HCID 23445281 | HCID 23445281 | — |
| Product | HCID 23445430 | HCID 23445430 | 34% |
Reaction Steps
N-(4-bromo-3-methyl-5-isoxazolyl)-2-(4-methyl-trans-styryl)thiophene-3-sulfonamide was prepared in the same manner as described in Example 2 by reaction of 2-(4-methyl-trans-styryl)thiophene-3-sulfonyl chloride with 5-amino-4-bromo-3-methylisoxazole. The crude product was purified by HPLC followed by crystallization resulting in a 34% yield, m.p. 101-105° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613804B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-4d00e47c91e9448db6fea447a00ef5bb |
| Source note | uspto-grants-2003_09 |