HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylbenzene-1-sulfonyl chloride → N-(4-Chloro-3-methyl-5-isoxazolyl)-2-biphenylsulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylbenzene-1-sulfonyl chloride | HCID 2756680 | — |
| Reactant | 4-Chloro-3-methyl-1,2-oxazol-5-amine | HCID 10582822 | — |
| Product | N-(4-Chloro-3-methyl-5-isoxazolyl)-2-biphenylsulfonamide | HCID 15453178 | 74% |
Reaction Steps
N-(4-Chloro-3-methyl-5-isoxazolyl)-2-biphenylsulfonamide was prepared in the same manner as described in Example 202 from 5-amino-4-chloro-3-methylisoxazole and 2-biphenylsulfonyl chloride in 74% yield. Purification was achieved by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 132-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613804B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-f70cac315e094391bf3e50e91fbea569 |
| Source note | uspto-grants-2003_09 |