HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Benzoic acid, 4-octyl-, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Benzoyl chloride, 4-octyl- | HCID 170865 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Benzoic acid, 4-octyl-, methyl ester | HCID 104715 | — |
Reaction Steps
4-Octylbenzoyl chloride (obtained by reacting 4-octylbenzoic acid with thionyl chloride) is esterified with methanol in the presence of an equimolar amount of triethylamine and 0.1 mol % of DMAP. Customary work-up followed by purification by distillation affords methyl 4-octylbenzoate as a colorless liquid, b.p. 112° C./0.25 mbar.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06616989B1 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-e4739e1df08249cc8e15da5aefd0e48e |
| Source note | uspto-grants-2003_09 |