HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22857780, compound → HCID 70024306, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22857780 | HCID 22857780 | — |
| Reactant | HCID 86625176 | HCID 86625176 | — |
| Reactant | HCID 135825021 | HCID 135825021 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 70024306 | HCID 70024306 | — |
Reaction Steps
3-(5-Butylthiophen-2-yl)-5-{4-[(S)-2-fluorodecyloxy]-phenyl}-isoxazole is prepared similar to Example 6, but 3-(5-butylthiophen-2-yl)-5-(4-hydroxyphenyl)-isoxazole is etherified with (S)-2-fluoro-1-decanol by the method of Mitsunobu (diethyl azodicarboxylate/triphenylphosphine in tetrahydrofuran; Synthesis 1981, 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06616989B1 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-e87463c1353a49c68669acd7652a201a |
| Source note | uspto-grants-2003_09 |