Potassium Carbonate → HCID 22995379, compound

Participants

Reaction Steps

A mixture of 1.7 g dipyridyl-methylchloride (14), 1 g N,N′-bis(pyrid-2-ylmethyl)-1,3-diamino-propane (15) and 0.5 g potassium carbonate in 20 ml acetonitrile was stirred and refluxed under argon for 48 h. TLC (silica/eluent CH2Cl2/MeOH(7N NH3) 90/10) indicated the reaction to be almost complete. The mixture was filtered and evaporated. The residue was chromatographed on silica using dichloromethane with increasing methanol concentration (up to 5%) to give 1.5 g pure product as a yellow/brown glassy gum.

Provenance & Evidence