HRID1167085

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[N+]1(CCN=C=NC2CCCCC2)CCOCC1.Cc1ccc(S(=O)(=O)[O-])cc1

HCID17220

4-(2-{[(Cyclohexylimino)methylidene]amino}ethyl)-4-methylmorpholin-4-ium 4-methylbenzene-1-sulfonate

C21H33N3O4S

HCID75263

Isopropyl isothiocyanate

C4H7NS

HCID2736755

1,2-Diamino-4,5-difluorobenzene

C6H6F2N2

PRODUCTS

生成物

HCID22995424

未命名化合物

收率 53%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

4,5-Difluoro-1,2-phenylenediamine (2.87 g, 19.91 mmol), isopropyl isothiocyanate (2.19 g, 21.65 mmol), 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate (11.38 g, 26.87 mmol) and pyridine (75 mL) were used according to general method I. The product was recrystallized from 1,4-dioxane to afford 2.23 g (53%) of a white solid; m.p. 188-189° C. Anal. Calcd for C10H11F2N3: C, 56.87; A, 5.25; N, 19.89. Found C, 56.95; H, 5.25; N, 19.98.

WORKUP

后处理

customThe product was recrystallized from 1,4-dioxane