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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1167102Generated: October 25, 2026

N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamide → Ethyl 2-ethyl-2-phenyl-5-{4-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-piperidin-1-yl}-pentanecarboxylate

https://huagongshe.com/reaction/1167102

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamideHCID 9928271—
ReactantEthyl 5-bromo-2-ethyl-2-phenyl-pentanecarboxylateHCID 22995755—
ProductEthyl 2-ethyl-2-phenyl-5-{4-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-piperidin-1-yl}-pentanecarboxylateHCID 22995672—

Reaction Steps

Prepared from 4′-trifluoromethyl-biphenyl-2-carboxylic acid-piperidin-4-ylamide and ethyl 5-bromo-2-ethyl-2-phenyl-pentanecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06617325B1
Source datasetuspto-grants-2003_09
ORD IDord-83dc4423f7a1447abb7d0766837bb013
Source noteuspto-grants-2003_09