Propionyl chloride → HCID 9881985, compound
Reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH2:14])=[CH:8][CH:7]=2)=[CH:2]1.[C:16](Cl)(=[O:19])[CH2:17][CH3:18]>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH:14][C:16](=[O:19])[CH2:17][CH3:18])=[CH:8][CH:7]=2)=[CH:2]1Participants
3
Procedure
The title compound was prepared from 2-(4-(3-thienyl)phenyl)propylamine (see example 14) and propionyl chloride in a manner analogous to the procedure described in example 14. The NMR spectrum was consistent with the proposed title structure.
Sources & evidence
- ORD record
- ord-5025e447503a4b2980e1da7ac234e953
- Source dataset
- uspto-grants-2003_09
- Patent number
- US06617351B1
Reaction notes
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