Nicotinoyl chloride → HCID 9949074, compound

HRID 1167232Notes

Reaction equation

[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH2:14])=[CH:8][CH:7]=2)=[CH:2]1.[C:16](Cl)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[N:19][CH:18]=1>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH:14][C:16](=[O:23])[C:17]3[CH:22]=[CH:21][CH:20]=[N:19][CH:18]=3)=[CH:8][CH:7]=2)=[CH:2]1

Participants

Reactant 2

HCID 82604Nicotinoyl chloride

HCID 10727517HCID 10727517, compound

Product 1

HCID 9949074HCID 9949074, compound

Procedure

The title compound was prepared from 2-(4-(3-thienyl)phenyl)propylamine (see example 14) and nicotinoyl chloride in a manner analogous to the procedure described in example 14. The NMR spectrum was, consistent with the proposed title structure.

Sources & evidence

ORD record: ord-bcaa5d4ca5ff4b88b67829c68e492db4
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06617351B1

Reaction notes

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