Pyridine-2-carbonyl chloride → HCID 9949075, compound

HRID 1167233Notes

Reaction equation

HRID 1167233 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH2:14])=[CH:8][CH:7]=2)=[CH:2]1.[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[C:22](Cl)=[O:23]>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH:14][C:22](=[O:23])[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][N:16]=3)=[CH:8][CH:7]=2)=[CH:2]1

Participants

3

Reactant 2

HCID 135034Pyridine-2-carbonyl chlorideHCID 10727517HCID 10727517, compound

Product 1

HCID 9949075HCID 9949075, compound

Procedure

The title compound was prepared 2-(4-(3-thienyl)phenyl)propylamine (see example 14) and picolinoyl chloride in a manner analogous to the procedure described in example 14. The NMR spectrum was consistent with the proposed title structure.

Sources & evidence

ORD record
ord-b241ecbf0313422da3bbbadcd925184c
Source dataset
uspto-grants-2003_09
Patent number
US06617351B1

Reaction notes

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