1-Pyrrolidinecarbonyl chloride → HCID 9839849, compound

HRID 1167237Notes

Reaction equation

HRID 1167237 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH2:14])=[CH:8][CH:7]=2)=[CH:2]1.[N:16]1([C:21](Cl)=[O:22])[CH2:20][CH2:19][CH2:18][CH2:17]1>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH:14][C:21]([N:16]3[CH2:20][CH2:19][CH2:18][CH2:17]3)=[O:22])=[CH:8][CH:7]=2)=[CH:2]1

Participants

3

Reactant 2

HCID 709371-Pyrrolidinecarbonyl chlorideHCID 10727517HCID 10727517, compound

Product 1

HCID 9839849HCID 9839849, compound

Procedure

The title compound was prepared from 2-(4-(3-thienyl)phenyl)propylamine (see example 14) and pyrrolidine carbonyl chloride in a manner analogous to the procedure described in example 14. The NMR spectrum was consistent with the proposed title structure.

Sources & evidence

ORD record
ord-9952abe6fbfe4259870c0e4196fafd99
Source dataset
uspto-grants-2003_09
Patent number
US06617351B1

Reaction notes

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