4-Morpholinecarbonyl chloride → HCID 9905570, compound

HRID 1167238Notes

Reaction equation

HRID 1167238 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH2:14])=[CH:8][CH:7]=2)=[CH:2]1.[N:16]1([C:22](Cl)=[O:23])[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH:12]([CH3:15])[CH2:13][NH:14][C:22]([N:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)=[O:23])=[CH:8][CH:7]=2)=[CH:2]1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 10727517HCID 10727517, compound

Product 1

HCID 9905570HCID 9905570, compound

Procedure

The title compound was prepared from 2-(4-(3-thienyl)phenyl)propylamine (see example 14) and 4-morpholine carbonyl chloride in a manner analogous to the procedure described in example 14. The NMR spectrum was consistent with the proposed title structure.

Sources & evidence

ORD record
ord-4aca53ad92c94668951b9fdc9bbc6a9a
Source dataset
uspto-grants-2003_09
Patent number
US06617351B1

Reaction notes

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