HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Ave-9488
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | 2-Aminoindan hydrochloride | HCID 122764 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ave-9488 | HCID 10131276 | — |
Reaction Steps
43.70 g (258 mol) 2-aminoindane hydrochloride and 53.43 g (528 mmol) triethylamine were mixed with 250 ml of tetrahydrofuran, 42.89 g (270 mmol) 4-fluorobenzoylchloride were added, and the mixture was stirred for 2 h at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06617359B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-6b577c98d7cb4a9aaed5d27f58738079 |
| Source note | uspto-grants-2003_09 |