Hydrochloric Acid → HCID 22996203, compound

Participants

Reaction Conditions

Reaction Steps

Hydrogen chloride gas was passed through a solution of 2-methoxy-benzonitrile (760 mg, 5.708 mmol) in anhydrous ethanol (125 mL) cooled to 0° C. After 3.5 h, hydrogen chloride gas was stopped and the reaction mixture was stirred at room temperature overnight. The solvent was removed and the residue was triturated in diethyl ether to afford ethyl 2-methoxy-benzimidate hydrochloride (865 mg, 70%). It was used without further purification.

Provenance & Evidence