HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → 2-Methoxycyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Dihydrocinchonidine | HCID 6914728 | — |
| Catalyst | Tetramethylammonium chloride | HCID 6379 | — |
| Product | 2-Methoxycyclohexanone | HCID 110998 | — |
Reaction Steps
Example 1 is repeated, except that isopropanol is used as solvent, 10 mg of hydrocinchonidine are used as modifier and 100 mg of catalyst are used. In addition, 800 mg of Amberlite IRA-900 (strongly basic anion exchanger, activated using NaOH) are added. The yield is 0.36 g of product of 95% purity containing 5% solvent (44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06617475B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-61d0b03ba9bd4e2c877b06e3ba56c223 |
| Source note | uspto-grants-2003_09 |