HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 69981530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | HCID 54214185 | HCID 54214185 | — |
| Product | HCID 69981530 | HCID 69981530 | 43.6% |
Reaction Steps
Using essentially the technique of Example 94, starting with 3-(4-(4-aminopiperidin-1-yl)-3-fluorophenyl)-5(R)-(isoxazol-3-yloxymethyl)oxazolidin-2-one (249 mg, 0.66 mmol) and methyl chloroformate (70 mg, 0.74 mmol) in place of methanesulfonyl choride, gave the desired product (125 mg) after chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06617339B1 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-8d0798eb543943538a6da43df8ea0318 |
| Source note | uspto-grants-2003_09 |