p-Fluoronitrobenzene → 5-(4-Nitrophenoxy)-3-chloropyridine

HRID 1167662노트

반응식

HRID 1167662 반응식
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[Cl:11][C:12]1[CH:13]=[N:14][CH:15]=[C:16]([OH:18])[CH:17]=1>>[Cl:11][C:12]1[CH:13]=[N:14][CH:15]=[C:16]([O:18][C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=2)[CH:17]=1

참가 물질

3

반응물 2

HCID 9590p-FluoronitrobenzeneHCID 5823053-Hydroxy-5-chloropyridine

생성물 1

HCID 121093595-(4-Nitrophenoxy)-3-chloropyridine수율 87.6%

실험 절차

4-Fluoro-nitrobenzene (5.0 g) and 3chloro-5-hydroxypyridine (4.59 g) were combined at 60° C. using a method similar to that of Example 21.2 to provide 7.78 g of 4-(3-chloro-5-pyridyloxy)nitrobenzene. mp 80-82° C.

후처리

  1. customwere combined at 60° C.

출처 및 근거

ORD 기록
ord-aefb5c8728c841a4a620f1f3e6a6f6ac
출처 데이터셋
uspto-grants-2003_09
특허 번호
US06620827B2

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