HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylene Glycol Monomethyl Ether → 2-[2-(2-Methoxy-ethoxy)-ethoxy]-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylene Glycol Monomethyl Ether | HCID 8134 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Chloro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide | HCID 11315694 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-[2-(2-Methoxy-ethoxy)-ethoxy]-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide | HCID 22993389 | — |
Reaction Steps
From 2-chloro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide with sodium hydride and diethylene glycol monomethyl ether in dioxane. ES-MS m/e (%): 511 (M+Na+, 13), 489 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06620811B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-24a1f82637a84422b7121bff74886d76 |
| Source note | uspto-grants-2003_09 |