Cesium carbonate → HCID 10115311, compound

HRID 1167752Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]([CH:25]=[CH:26][N:27]=1)[C:5]([NH:7][C:8]1[S:9][C:10]2[C:16]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[CH:15][CH:14]=[C:13]([O:23][CH3:24])[C:11]=2[N:12]=1)=[O:6].C(=O)([O-])[O-].[Cs+].[Cs+].[CH2:34]([O:36][CH2:37][CH2:38][NH2:39])[CH3:35]>>[CH2:34]([O:36][CH2:37][CH2:38][NH:39][C:2]1[CH:3]=[C:4]([CH:25]=[CH:26][N:27]=1)[C:5]([NH:7][C:8]1[S:9][C:10]2[C:16]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[CH:15][CH:14]=[C:13]([O:23][CH3:24])[C:11]=2[N:12]=1)=[O:6])[CH3:35]

Participants

Reactant 3

HCID 10796Cesium carbonate

HCID 66970Ethoxyethylamine

HCID 229934292-bromo-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide

Product 1

HCID 10115311HCID 10115311, compound

Procedure

From 2-bromo-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-y)-isonicotinamide with cesium carbonate and 2-ethoxyethylamine. ES-MS m/e (%): 458 (M+H+, 100).

Sources & evidence

ORD record: ord-926a8e5dac9c45f9ac08b85b7ea307e7
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06620811B2

Reaction notes

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