Cesium carbonate → HCID 22993434, compound

HRID 1167795Notes

Reaction equation

HRID 1167795 reaction equation
Cl[C:2]1[CH:27]=[CH:26][C:5]([C:6]([NH:8][C:9]2[S:10][C:11]3[C:17]([N:18]4[CH2:23][CH2:22][O:21][CH2:20][CH2:19]4)=[CH:16][CH:15]=[C:14]([O:24][CH3:25])[C:12]=3[N:13]=2)=[O:7])=[CH:4][N:3]=1.C(=O)([O-])[O-].[Cs+].[Cs+].[CH3:34][O:35][CH2:36][CH2:37][NH:38][CH2:39][CH3:40]>>[CH2:39]([N:38]([CH2:37][CH2:36][O:35][CH3:34])[C:2]1[CH:27]=[CH:26][C:5]([C:6]([NH:8][C:9]2[S:10][C:11]3[C:17]([N:18]4[CH2:23][CH2:22][O:21][CH2:20][CH2:19]4)=[CH:16][CH:15]=[C:14]([O:24][CH3:25])[C:12]=3[N:13]=2)=[O:7])=[CH:4][N:3]=1)[CH3:40]

Participants

4

Reactant 3

HCID 10796Cesium carbonateHCID 546877N-(2-Methoxyethyl)ethylamineHCID 22993400HCID 22993400, compound

Product 1

HCID 22993434HCID 22993434, compound

Procedure

From 6-chloro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-nicotinamide with cesium carbonate and N-(2-methoxyethyl)ethylamine. ES-MS m/e (%): 472 (M+H+, 100).

Sources & evidence

ORD record
ord-9456a8a056434e45bb289b33e51abdee
Source dataset
uspto-grants-2003_09
Patent number
US06620811B2

Reaction notes

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