Boron tribromide → HCID 22274632, compound

HRID 1167851Notes

Reaction equation

C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][C:10]=2[CH3:17])=[CH:5][CH:4]=1.B(Br)(Br)Br>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][C:10]=2[CH3:17])=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 25134Boron tribromide

HCID 22994375HCID 22994375, compound

Product 1

HCID 22274632HCID 22274632, compoundYield 98%

Procedure

The product from Example 165A and 1.0M BBr3 were processed as described in Example 164B to provide the title compound (98% yield). 1HNMR (300 MHz, CDCl3) δ2.42 (s, 3H), 5.2 (s, 1H), 6.70-7.54 (m, 7H); MS (DCI) m/z 210 (M+H)+.

Sources & evidence

ORD record: ord-1fd292371f8b4601808aa5c812ba700b
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06620839B2

Reaction notes

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