Boron tribromide → HCID 15065645, compound

HRID 1167855Notes

Reaction equation

HRID 1167855 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16]C)=[CH:12][CH:11]=2)[CH:5]=[CH:6][C:7]=1[C:8]#[N:9].B(Br)(Br)Br>>[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH:5]=[CH:6][C:7]=1[C:8]#[N:9]

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 27633572-fluoro-4-(4-methoxyphenyl)benzonitrile

Product 1

HCID 15065645HCID 15065645, compoundYield 95%

Procedure

The product from Example 166A and 1.0M BBr3 were processed as described in Example 164B to provide the title compound (95% yield). 1HNMR (300 MHz, CDCl3) δ4.95 (s, 3H), 6.80-7-55 (m, 7H); MS (DCI) m/z 214 (M+H)+.

Sources & evidence

ORD record
ord-e26f6de9b97443cdaa1c7f993ab1f745
Source dataset
uspto-grants-2003_09
Patent number
US06620839B2

Reaction notes

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