Benzaldehyde → HCID 59047018, compound

Participants

Reaction Steps

A solution of KOH 50% (3 ml) is added to an equimolar solution of 7-(3-methylbut -2-enyloxy)-8-acetyl-3-methylflavone (2.71 g, 0.0075 mol) and benzaldehyde (0.8 g, 0.0075 mol) in ethanol 95%; the addition is performed under energetic stirring at room temperature. The reaction is left under stirring for one night and then diluted with water and acidified; the precipitate is separated by filtration and dried under vacuum. The compound is crystallized by methanol to give 2.3 g of product m.p. 83-84° C., 1H-NMR (CDCl3)δ:1.67 (s, 3H); 1.70 (s, 3H); 2.18 (5, 3H); 4.68 (d, 2H, J=6.4 Hz); 5.30-5.38 (m, 11H); 7.00 (d, 1H, J=16 Hz); 7.02 (d, 11, J=8.9 Hz; 7.24 (d, 1H, J=16 Hz); 7.30-7.45 (m, 6H); 7.48-7.54 (m, 4H);8.30 (d, 1H, J=8.9 Hz).

Provenance & Evidence