HCID 56992784, compound → HCID 57076224, compound

HRID 1167939Notes

Reaction equation

[C:1]([O:5][C:6](=[O:21])[CH2:7][C@@H:8]([CH2:17][N:18]=[N+:19]=[N-:20])[CH2:9][C@H:10]([CH3:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])([CH3:4])([CH3:3])[CH3:2].C(OC(=O)C[C@@H](COS(C1C=CC(C)=CC=1)(=O)=O)C[C@@H](C)CCCCC)(C)(C)C>>[C:1]([O:5][C:6](=[O:21])[CH2:7][C@@H:8]([CH2:17][N:18]=[N+:19]=[N-:20])[CH2:9][C@@H:10]([CH3:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])([CH3:3])([CH3:4])[CH3:2]

Participants

Reactant 2

HCID 56992784HCID 56992784, compound

HCID 57302665HCID 57302665, compound

Product 1

HCID 57076224HCID 57076224, compoundYield 96%

Procedure

A procedure similar to that used to prepare compound 160 was used except (3S,5S)-5-methyl-3-(toluene-4-sulfonyloxymethyl)-decanoic acid tert-butyl ester 168 (4.155 g, 9.74 mmol) was used as a reactant to give 169 as an oil (2.77 g, 96%). MS (APCI) m/z 270 (M+−27, 30%, -N2), 214 (M+−87, 100%, -tBu, -N2).

Sources & evidence

ORD record: ord-ebb67b469be74f0ebb4575a7f4da3eac
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06620829B2

Reaction notes

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