HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyryl chloride → 3-Methyl-4-butyrylaminobenzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyryl chloride | HCID 8855 | — |
| Reactant | Methyl 4-amino-3-methylbenzoate | HCID 2736799 | — |
| Product | 3-Methyl-4-butyrylaminobenzoic acid methyl ester | HCID 9856104 | — |
Reaction Steps
In J. Med. Chem. 1993, 4040 a synthesis of the antagonist is described which starts from methyl 4-amino-3-methylbenzoate (I) and reacts it with butyryl chloride to give methyl N-butyryl-4-amino-3-methylbenzoate (II) (see the following reaction scheme (1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06620962B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-d0155eaf81914d6882258581dfc07848 |
| Source note | uspto-grants-2003_09 |