HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidinedione → Edaglitazone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidinedione | HCID 5437 | — |
| Reactant | 4-[2-(7-Bromomethyl-benzo[b]thiophen-4-yloxy)-ethyl]-5-methyl-2-phenyl-oxazole | HCID 11441750 | — |
| Product | Edaglitazone | HCID 9825701 | — |
Reaction Steps
reacting 4-[2-(7-Bromomethyl-benzo[b]thiophen-4-yloxy)-ethyl]-5-methyl-2-phenyl-oxazole with 2,4-thiazolidinedione (commercially available) to give 5-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophen-7-ylmethyl}2,4-thiazolidinedione,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06620941B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-273e21ff30fe43858723d6a796fc1fed |
| Source note | uspto-grants-2003_09 |