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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168070Generated: October 29, 2026

Thiazolidinedione → Edaglitazone

https://huagongshe.com/reaction/1168070

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazolidinedioneHCID 5437—
Reactant4-[2-(7-Bromomethyl-benzo[b]thiophen-4-yloxy)-ethyl]-5-methyl-2-phenyl-oxazoleHCID 11441750—
ProductEdaglitazoneHCID 9825701—

Reaction Steps

reacting 4-[2-(7-Bromomethyl-benzo[b]thiophen-4-yloxy)-ethyl]-5-methyl-2-phenyl-oxazole with 2,4-thiazolidinedione to give 5-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophen-7-ylmethyl}2,4-thiazolidinedione,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06620941B2
Source datasetuspto-grants-2003_09
ORD IDord-ace497f7393741baaef5e495fe15ca8c
Source noteuspto-grants-2003_09