3-Methoxypropanoyl chloride → HCID 22992243, compound

HRID 1168164Notes

Reaction equation

HRID 1168164 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13](=[O:23])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][NH:21][CH3:22])=[CH:16][CH:15]=3)[S:11][C:7]=2[C:6]([N:24]2[CH2:29][CH2:28][O:27][CH2:26][CH2:25]2)=[CH:5][CH:4]=1.[CH3:30][O:31][CH2:32][CH2:33][C:34](Cl)=[O:35]>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13](=[O:23])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][N:21]([C:34](=[O:35])[CH2:33][CH2:32][O:31][CH3:30])[CH3:22])=[CH:16][CH:15]=3)[S:11][C:7]=2[C:6]([N:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 27597283-Methoxypropanoyl chlorideHCID 10295168HCID 10295168, compound

Product 1

HCID 22992243HCID 22992243, compound

Procedure

Using N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-4-methylaminomethyl-benzamide and 3-methoxy-propionyl chloride, the title compound was prepared as light yellow crystals (46% yield). MS: m/e=499(M+H+).

Sources & evidence

ORD record
ord-faa92290efcd4b18a365aa34852697cb
Source dataset
uspto-grants-2003_09
Patent number
US06624163B2

Reaction notes

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