3-Methoxypropanoyl chloride → HCID 22992245, compound

HRID 1168168Notes

Reaction equation

HRID 1168168 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13](=[O:22])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][NH2:21])=[CH:16][CH:15]=3)[S:11][C:7]=2[C:6]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[CH:5][CH:4]=1.[CH3:29][O:30][CH2:31][CH2:32][C:33](Cl)=[O:34]>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13](=[O:22])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][NH:21][C:33](=[O:34])[CH2:32][CH2:31][O:30][CH3:29])=[CH:16][CH:15]=3)[S:11][C:7]=2[C:6]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 27597283-Methoxypropanoyl chlorideHCID 11280971HCID 11280971, compound

Product 1

HCID 22992245HCID 22992245, compound

Procedure

Using N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-4-aminomethyl-benzamide and 3-methoxy-propionyl chloride, the title compound was prepared as white crystals (44% yield). MS: m/e=485(M+H+).

Sources & evidence

ORD record
ord-0f3ca2a9ed324c3eb68bcd8ef3a66f29
Source dataset
uspto-grants-2003_09
Patent number
US06624163B2

Reaction notes

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