Methoxyacetyl chloride → HCID 22992248, compound

HRID 1168173Notes

Reaction equation

HRID 1168173 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13](=[O:24])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][NH:21][CH2:22][CH3:23])=[CH:16][CH:15]=3)[S:11][C:7]=2[C:6]([N:25]2[CH2:30][CH2:29][O:28][CH2:27][CH2:26]2)=[CH:5][CH:4]=1.[CH3:31][O:32][CH2:33][C:34](Cl)=[O:35]>>[CH2:22]([N:21]([CH2:20][C:17]1[CH:18]=[CH:19][C:14]([C:13]([NH:12][C:10]2[S:11][C:7]3[C:6]([N:25]4[CH2:26][CH2:27][O:28][CH2:29][CH2:30]4)=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[C:8]=3[N:9]=2)=[O:24])=[CH:15][CH:16]=1)[C:34](=[O:35])[CH2:33][O:32][CH3:31])[CH3:23]

Participants

3

Reactant 2

HCID 96623Methoxyacetyl chlorideHCID 22992246HCID 22992246, compound

Product 1

HCID 22992248HCID 22992248, compound

Procedure

Using N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-4-ethylaminomethyl-benzamide and methoxy-acetyl chloride, the title compound was prepared as white solid (33% yield). MS: m/e=499(M+H+).

Sources & evidence

ORD record
ord-f60e231af454493dac0e20af82dd69e5
Source dataset
uspto-grants-2003_09
Patent number
US06624163B2

Reaction notes

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