5-AMINO-6-CHLORO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE → 5-Amino-6-chloro-2-ethyl-N-{1-[3-(methoxy)propyl]4-piperidinyl}imidazo[1,2-a]pyridine-8-carboxamide

HRID 1168252Notes

Reaction equation

HRID 1168252 reaction equation
[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH3:12])[N:10]=[C:6]2[C:5]([C:13]([OH:15])=O)=[CH:4][C:3]=1[Cl:16].NC1N2C=CN=C2C(C([NH:29][CH:30]2[CH2:35][CH2:34][N:33]([CH2:36][CH2:37][CH2:38][O:39][CH3:40])[CH2:32][CH2:31]2)=O)=CC=1Cl>>[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH3:12])[N:10]=[C:6]2[C:5]([C:13]([NH:29][CH:30]2[CH2:35][CH2:34][N:33]([CH2:36][CH2:37][CH2:38][O:39][CH3:40])[CH2:32][CH2:31]2)=[O:15])=[CH:4][C:3]=1[Cl:16]

Participants

3

Reactant 2

HCID 120880945-AMINO-6-CHLORO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDEHCID 222364965-Amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxylic acid

Product 1

HCID 229922325-Amino-6-chloro-2-ethyl-N-{1-[3-(methoxy)propyl]4-piperidinyl}imidazo[1,2-a]pyridine-8-carboxamide

Procedure

The title compound was prepared according to the procedure described in the step 3 in EXAMPLE 5 using 5-amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 10, Step 2) and 1-[3-(methyloxy)propyl]-4-piperidinamine (EXAMPLE 3).

Sources & evidence

ORD record
ord-e97a9d7861e74fadad630449ffc55c1e
Source dataset
uspto-grants-2003_09
Patent number
US06624162B2

Reaction notes

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