5-AMINO-6-CHLORO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE → 5-Amino-6-chloro-2-propyl-n-{1-[3-(methoxy)propyl]-4-piperidinyl}imidazo[1,2-a]pyridine-8-carboxamide

HRID 1168258Notes

Reaction equation

HRID 1168258 reaction equation
[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH2:12][CH3:13])[N:10]=[C:6]2[C:5]([C:14]([OH:16])=O)=[CH:4][C:3]=1[Cl:17].NC1N2C=CN=C2C(C([NH:30][CH:31]2[CH2:36][CH2:35][N:34]([CH2:37][CH2:38][CH2:39][O:40][CH3:41])[CH2:33][CH2:32]2)=O)=CC=1Cl>>[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH2:12][CH3:13])[N:10]=[C:6]2[C:5]([C:14]([NH:30][CH:31]2[CH2:36][CH2:35][N:34]([CH2:37][CH2:38][CH2:39][O:40][CH3:41])[CH2:33][CH2:32]2)=[O:16])=[CH:4][C:3]=1[Cl:17]

Participants

3

Reactant 2

HCID 120880945-AMINO-6-CHLORO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDEHCID 229922285-Amino-6-chloro-2-propylimidazo[1,2-a]pyridine-8-carboxylic acid

Product 1

HCID 229922155-Amino-6-chloro-2-propyl-n-{1-[3-(methoxy)propyl]-4-piperidinyl}imidazo[1,2-a]pyridine-8-carboxamide

Procedure

The title compound was prepared according to the procedure described in the step 3 in EXAMPLE 5 using 5-amino-6-chloro-2-propylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 16, Step 2) and 1-[3-(methyloxy)propyl]-4-piperidinamine (EXAMPLE 3).

Sources & evidence

ORD record
ord-5fa8f4cb812c4ffda0e3f509afec0547
Source dataset
uspto-grants-2003_09
Patent number
US06624162B2

Reaction notes

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