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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168260Generated: November 3, 2026

Dichloromethane → 5-Amino-6-chloro-2-isopropylimidazo[1,2-a]pyridine-8-carboxylic acid

https://huagongshe.com/reaction/1168260

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantMethyl 5-amino-6-chloro-2-isopropylimidazo[1,2-a]pyridine-8-carboxylateHCID 22992220—
SolventMethanolHCID 887—
Product5-Amino-6-chloro-2-isopropylimidazo[1,2-a]pyridine-8-carboxylic acidHCID 22992221—

Reaction Steps

The title compound was prepared according to the procedure described in the step 4 in EXAMPLE 1 (METHOD A) from methyl 5-amino-6-chloro-2-isopropylimidazo[1,2-a]pyridine-8-carboxylate (EXAMPLE 20, Step 1). Rf value: 0.33 (CH2Cl2:MeOH, 20:1, v/v)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624162B2
Source datasetuspto-grants-2003_09
ORD IDord-fb7b5c92304f4f478891f1b243f7a34e
Source noteuspto-grants-2003_09