(2S,3R,4R,5S)-2,4-bis(acetoxy)-5-(3-ethyl-1,2,4-oxadiazol-5-yl)tetrahydro-3-furanyl acetate → (2R,3R,4S,5S)-4-(Acetyloxy)-2-(6-[(2,2-diphenylethyl)amino]-2-{[(isobutylsulphonyl)amino]methyl}-9H-purin-9-yl)-5-(3-ethyl-1,2,4-oxadiazol-5-yl)tetrahydro-3-furanyl Acetate

Participants

Reaction Steps

Prepared by the same method as Preparation 26 from N-({6-[(2,2-diphenylethyl)amino]-9H-purin-2-yl}methyl)-2-methyl-1-propanesulphonamide hydrochloride (Preparation 8) and a mixture of (2R,3R,4R,5S)-2,4-bis(acetoxy)-5-(3-ethyl-1,2,4-oxadiazol-5-yl)tetrahydro-3-furanyl acetate and (2S,3R,4R,5S)-2,4-bis(acetoxy)-5-(3-ethyl-1,2,4-oxadiazol-5-yl)tetrahydro-3-furanyl acetate (Preparation 14).

Provenance & Evidence