HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,3R,4R, 5R)-3,4-bis(benzoyloxy)-5-(1-ethyl-1H-1,2,3-triazol-4-yl)tetrahydro-2-furanyl benzoate → (2R,3R,4R,5R)-4-(Benzoyloxy)-5-(6-[(2,2-diphenylethyl)amino]-2-{[(isobutylsulphonyl)amino]methyl}-9H-purin-9-yl)-2-(1-ethyl-1H-1,2,3-triazol-4-yl)tetrahydro-3-furanyl benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,3R,4R, 5R)-3,4-bis(benzoyloxy)-5-(1-ethyl-1H-1,2,3-triazol-4-yl)tetrahydro-2-furanyl benzoate | HCID 59094505 | — |
| Reactant | HCID 178455636 | HCID 178455636 | — |
| Product | (2R,3R,4R,5R)-4-(Benzoyloxy)-5-(6-[(2,2-diphenylethyl)amino]-2-{[(isobutylsulphonyl)amino]methyl}-9H-purin-9-yl)-2-(1-ethyl-1H-1,2,3-triazol-4-yl)tetrahydro-3-furanyl benzoate | HCID 59094540 | — |
Reaction Steps
Prepared by the same method as Preparation 26 from N-({6-[(2,2-diphenylethyl)amino]-9H-purin-2-yl}methyl)-2-methyl-1-propanesulphonamide hydrochloride (Preparation 8) and (2S,3R,4R, 5R)-3,4-bis(benzoyloxy)-5-(1-ethyl-1H-1,2,3-triazol-4-yl)tetrahydro-2-furanyl benzoate (Preparation 25).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06624158B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-fe6e357ea9c947bfa1cb563f03268e0e |
| Source note | uspto-grants-2003_09 |