HRID1168311

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCn1nnc([C@H]2OC(OC(C)=O)[C@H](OC(C)=O)[C@@H]2OC(C)=O)n1

HCID11302289

未命名化合物

结构：CC(C)N(CCNC(=O)NCc1nc(NCC(c2ccccc2)c2ccccc2)c2nc[nH]c2n1)C1CCCC1

HCID178457404

未命名化合物

PRODUCTS

生成物

结构：CCn1nnc([C@H]2O[C@@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(CNC(=O)NCCN(C(C)C)C5CCCC5)nc43)[C@H](OC(C)=O)[C@@H]2OC(C)=O)n1

HCID69978470

未命名化合物

PROCEDURE

实验过程

Prepared from N-{2-[cyclopentyl(isopropyl)amino]ethyl}-N′-({6-[(2,2-diphenyl-ethyl)amino]-9H-purin-2-yl}methyl)urea (Preparation 44) and (2R,3R,4R)-4,5-bis(acetoxy)-2-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3-furanyl acetate (WO 9967265) by a similar procedure to Preparation 26. The title compound was obtained as a white solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6ca472aacfa94c23b611d5c8dd1f1e2e
来源数据集: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06624158B2
来源说明: uspto-grants-2003_09

反应 SMILES

[CH:1]1([N:6]([CH:38]([CH3:40])[CH3:39])[CH2:7][CH2:8][NH:9][C:10]([NH:12][CH2:13][C:14]2[N:22]=[C:21]3[C:17]([N:18]=[CH:19][NH:20]3)=[C:16]([NH:23][CH2:24][CH:25]([C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[N:15]=2)=[O:11])[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:41]([O:44][C@H:45]1[C@@H:49]([O:50][C:51](=[O:53])[CH3:52])[CH:48](OC(=O)C)[O:47][C@@H:46]1[C:58]1[N:59]=[N:60][N:61]([CH2:63][CH3:64])[N:62]=1)(=[O:43])[CH3:42]>>[C:51]([O:50][C@@H:49]1[C@H:45]([O:44][C:41](=[O:43])[CH3:42])[C@@H:46]([C:58]2[N:59]=[N:60][N:61]([CH2:63][CH3:64])[N:62]=2)[O:47][C@H:48]1[N:20]1[CH:19]=[N:18][C:17]2[C:21]1=[N:22][C:14]([CH2:13][NH:12][C:10]([NH:9][CH2:8][CH2:7][N:6]([CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[CH:38]([CH3:40])[CH3:39])=[O:11])=[N:15][C:16]=2[NH:23][CH2:24][CH:25]([C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=1)[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1)(=[O:53])[CH3:52]