HRID1168312

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCn1nnc([C@H]2OC(OC(C)=O)[C@H](OC(C)=O)[C@@H]2OC(C)=O)n1

HCID11302289

未命名化合物

结构：O=C(NCCN1CCCCC1)NCc1nc(NCC(c2ccccc2)c2ccccc2)c2nc[nH]c2n1

HCID178523406

未命名化合物

PRODUCTS

生成物

结构：CCn1nnc([C@H]2O[C@@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(CNC(=O)NCCN5CCCCC5)nc43)[C@H](OC(C)=O)[C@@H]2OC(C)=O)n1

HCID59094530

未命名化合物

PROCEDURE

实验过程

Prepared from N-({6-[(2,2-diphenylethyl)amino]-9H-purin-2-yl}methyl)-N′-[2-(1-piperidinyl)ethyl]urea (Preparation 42) and (2R,3R,4R)-4,5-bis(acetoxy)-2-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3-furanyl acetate (WO 9967265) by a similar procedure to Preparation 26. The title compound was obtained as a white solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bb31d1d6c21b457a9195e12cd5e460e5
来源数据集: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06624158B2
来源说明: uspto-grants-2003_09

反应 SMILES

[C:1]1([CH:7]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH2:8][NH:9][C:10]2[N:18]=[C:17]([CH2:19][NH:20][C:21]([NH:23][CH2:24][CH2:25][N:26]3[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]3)=[O:22])[N:16]=[C:15]3[C:11]=2[N:12]=[CH:13][NH:14]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:38]([O:41][C@H:42]1[C@@H:46]([O:47][C:48](=[O:50])[CH3:49])[CH:45](OC(=O)C)[O:44][C@@H:43]1[C:55]1[N:56]=[N:57][N:58]([CH2:60][CH3:61])[N:59]=1)(=[O:40])[CH3:39]>>[C:48]([O:47][C@@H:46]1[C@H:42]([O:41][C:38](=[O:40])[CH3:39])[C@@H:43]([C:55]2[N:56]=[N:57][N:58]([CH2:60][CH3:61])[N:59]=2)[O:44][C@H:45]1[N:14]1[CH:13]=[N:12][C:11]2[C:15]1=[N:16][C:17]([CH2:19][NH:20][C:21]([NH:23][CH2:24][CH2:25][N:26]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1)=[O:22])=[N:18][C:10]=2[NH:9][CH2:8][CH:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)(=[O:50])[CH3:49]