p-Toluenesulfonic acid → HCID 86584532, compound

Participants

Reaction Steps

5 g of (d) was dissolved in 125 ml of a methanol/dichloromethane mixture (30:70) containing 4% (m/v) of para-toluene sulphonic acid (PTSA). This was stirred at ambient temperature for 3 h. The reaction mixture was then neutralised, washed with water and dried. After evaporating off the solvents, the crude product obtained was purified over silica to produce a white solid: 2 g (yield: 62%).

Provenance & Evidence