Water → HCID 86584533, compound

Participants

Reaction Conditions

Reaction Steps

9.5 g of (e) and 5 g of octanoyl chloride in 150 ml of toluene was heated under reflux at 90-95° C. for 4 h. After cooling, the reaction mixture was poured into 600 ml of water and extracted with toluene. The organic phases were combined, washed with NaHCO3 then with water. Finally, after drying and evaporating off the solvents, the crude product was purified over silica to recover 8.6 g of (f) (Yield: 70%).

Provenance & Evidence