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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168443Generated: October 25, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-{3-(2-(3-Bromophenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic acid

https://huagongshe.com/reaction/1168443

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant2-(3-Bromophenyl)-4-iodomethyl-5-methyloxazoleHCID 22493647—
Product2-{3-(2-(3-Bromophenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic acidHCID 22493653—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-bromophenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 51 of molecular weight 514.42, (C26H28BrNO5), MS(ESI): 514.30, 516.30 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624185B2
Source datasetuspto-grants-2003_09
ORD IDord-416db45faa6346bbb2a0ae8deb2213a4
Source noteuspto-grants-2003_09